I have a fully functional Hackintosh running OS X Lion 10.7.3 (11D50b) using the EP45T-USB3P Motherboard and the 9500GT video card.
Typical Problems I have had in previous OS X versions, but overcome easily in Lion 10.7.3 thanks to TonyMacx86:
Open GL working
Follow the instuctions at the following website:
Use the following settings on Multibeast 4.2.1
Unzip and put the resulting file in your /System/Library/Extensions Folder:
Repair Permissions and delete create new cache. Use this program for doing that easily: